Although adult stem cells exist in many tissues, their numbers are small, perhaps one adult stem cell for every 100,000 surrounding cells. These stem cells look like
Adult stem cells are undifferentiated cells, found throughout the body after development, that multiply by cell division to replenish dying cells and regenerate
Stem Cell Plasticity. Fig. 1. Stem cell plasticity could provide an alternative pathway for cancer development as seen in experimental gastric carcinogenesis.
origins of any differentiating cell following a tissue trans-plant. A second mechanism to explain stem cell plasticity is that direct cell fusion of a less
The relationship of the cells at the origin of the stem cells plasticity with a new type of mesodermal The discovery of the adult stem cell plasticity
Abstract There has been unprecedented recent interest in stem cells, mainly because of the hope they offer for cell therapy. Adult stem cells are an attractive source
reports of adult stem cell plasticity was published with substantial fanfare adult stem cells, I consider here only those that have been involved in plasticity
How to Cite. Poulsom, R., Alison, M. R., Forbes, S. J. and Wright, N. A. (2002), Adult stem cell plasticity. J. Pathol., 197: 441–456. doi: 10.1002/path.1176
Recent years have seen much excitement over the possibility that adult mammalian stem cells may be capable of differentiating across tissue lineage boundaries,
Adult Stem Cell Plasticity. It was not until recently that anyone seriously considered the possibility that stem cells in adult tissues could generate the